Assessment of Apoptosis by Immunohistochemistry to Active Caspase-3, Active Caspase-7, or Cleaved PARP in Monolayer Cells and Spheroid and Subcutaneous Xenografts of Human Carcinoma

Immunohistochemistry to active caspase-3, recently recommended for apoptosis detection, is inappropriate to detect apoptosis involving caspase-7. Cleavage of poly-ADP-ribose polymerase 1 (PARP-1), a major substrate of both caspases, is a valuable marker of apoptosis. Apoptosis evaluation induced in...

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Hlavní autoři: Bressenot, Aude, Marchal, Sophie, Bezdetnaya, Lina, Garrier, Julie, Guillemin, François, Plénat, François
Médium: Artigo
Jazyk:Inglês
Vydáno: Histochemical Society 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664986/
https://ncbi.nlm.nih.gov/pubmed/19029405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2008.952044
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