Compartmental targeting for mTHPC based photodynamic treatment in vivo: correlation between efficiency, pharmacokinetics and regional distribution of apoptosis

PURPOSE: The present study investigates the efficacy of compartmental targeting in grafted tumours treated by meta-tetra (hydroxyphenyl) chlorin (mTHPC) mediated photodynamic therapy (PDT). The therapeutic efficacy was further related to a regional photoinduced distribution of apoptosis and mTHPC bi...

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Detalhes bibliográficos
Main Authors: Garrier, Julie, Bressenot, Aude, Gräfe, Susanna, Marchal, Sophie, Mitra, Soumya, Foster, Thomas H., Guillemin, François, Bezdetnaya, Lina
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939317/
https://ncbi.nlm.nih.gov/pubmed/20656417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2010.04.009
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