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Heterochronic Shift in Hox-Mediated Activation of Sonic hedgehog Leads to Morphological Changes during Fin Development

We explored the molecular mechanisms of morphological transformations of vertebrate paired fin/limb evolution by comparative gene expression profiling and functional analyses. In this study, we focused on the temporal differences of the onset of Sonic hedgehog (Shh) expression in paired appendages a...

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Détails bibliographiques
Auteurs principaux: Sakamoto, Koji, Onimaru, Koh, Munakata, Keijiro, Suda, Natsuno, Tamura, Mika, Ochi, Haruki, Tanaka, Mikiko
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664896/
https://ncbi.nlm.nih.gov/pubmed/19365553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005121
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