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Developmental hourglass and heterochronic shifts in fin and limb development

How genetic changes are linked to morphological novelties and developmental constraints remains elusive. Here, we investigate genetic apparatuses that distinguish fish fins from tetrapod limbs by analyzing transcriptomes and open-chromatin regions (OCRs). Specifically, we compared mouse forelimb bud...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Onimaru, Koh, Tatsumi, Kaori, Tanegashima, Chiharu, Kadota, Mitsutaka, Nishimura, Osamu, Kuraku, Shigehiro
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932699/
https://ncbi.nlm.nih.gov/pubmed/33560225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62865
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