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Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects
Our knowledge of the major mechanisms underlying the effect of food on drug absorption allows reliable qualitative prediction based on biopharmaceutical properties, which can be assessed during the pre-clinical phase of drug discovery. Furthermore, several recent examples have shown that physiologic...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer US
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664880/ https://ncbi.nlm.nih.gov/pubmed/19184451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9079-7 |
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