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Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects
Our knowledge of the major mechanisms underlying the effect of food on drug absorption allows reliable qualitative prediction based on biopharmaceutical properties, which can be assessed during the pre-clinical phase of drug discovery. Furthermore, several recent examples have shown that physiologic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664880/ https://ncbi.nlm.nih.gov/pubmed/19184451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9079-7 |
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