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Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects

Our knowledge of the major mechanisms underlying the effect of food on drug absorption allows reliable qualitative prediction based on biopharmaceutical properties, which can be assessed during the pre-clinical phase of drug discovery. Furthermore, several recent examples have shown that physiologic...

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書誌詳細
主要な著者: Parrott, N., Lukacova, V., Fraczkiewicz, G., Bolger, M. B.
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664880/
https://ncbi.nlm.nih.gov/pubmed/19184451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9079-7
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