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Predicting Pharmacokinetics of Drugs Using Physiologically Based Modeling—Application to Food Effects

Our knowledge of the major mechanisms underlying the effect of food on drug absorption allows reliable qualitative prediction based on biopharmaceutical properties, which can be assessed during the pre-clinical phase of drug discovery. Furthermore, several recent examples have shown that physiologic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Parrott, N., Lukacova, V., Fraczkiewicz, G., Bolger, M. B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664880/
https://ncbi.nlm.nih.gov/pubmed/19184451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-008-9079-7
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