ANIT-Induced Intrahepatic Cholestasis Alters Hepatobiliary Transporter Expression via Nrf2-Dependent and Independent Signaling

Alpha-naphthylisothiocyanate (ANIT) causes intrahepatic cholestasis by injuring biliary epithelial cells. Adaptive regulation of hepatobiliary transporter expression has been proposed to reduce liver injury during cholestasis. Recently, the oxidative stress transcription factor Nrf2 (nf-e2–related f...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tanaka, Yuji, Aleksunes, Lauren M., Cui, Yue Julia, Klaassen, Curtis D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Biotransformation and Toxicokinetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664692/
https://ncbi.nlm.nih.gov/pubmed/19181614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp020
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