Termination of NF-κB activity through a gammaherpesvirus protein that assembles an EC(5)S ubiquitin-ligase

Host colonisation by lymphotropic gammaherpesviruses depends critically on the expansion of viral genomes in germinal centre (GC) B cells. Yet, host and virus molecular mechanisms involved in driving such proliferation remain largely unknown. Here, we show that the ORF73 protein encoded by the murid...

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Detalhes bibliográficos
Main Authors: Rodrigues, Lénia, Filipe, Josina, Seldon, Mark P, Fonseca, Lidia, Anrather, Josef, Soares, Miguel P, Simas, J Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664658/
https://ncbi.nlm.nih.gov/pubmed/19322197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.74
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