BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer

BTG3/ANA/APRO4 has been reported to be a tumor suppressor gene in some malignancies. It constitutes important negative regulatory mechanism for Src-mediated signaling, a negative regulator of the cell cycle and inhibits transcription factor E2F1. We report that BTG3 is downregulated in renal cancer...

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Autores principales: Majid, Shahana, Dar, Altaf A., Ahmad, Ardalan E., Hirata, Hiroshi, Kawakami, Kazumori, Shahryari, Varahram, Saini, Sharanjot, Tanaka, Yuichiro, Dahiya, Angela V., Khatri, Gaurav, Dahiya, Rajvir
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2009
Materias:
Cancer Prevention
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664457/
https://ncbi.nlm.nih.gov/pubmed/19221000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp042
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