MicroRNA-466 inhibits tumor growth and bone metastasis in prostate cancer by direct regulation of osteogenic transcription factor RUNX2

MicroRNAs (miRNAs) have emerged as key players in cancer progression and metastatic initiation yet their importance in regulating prostate cancer (PCa) metastasis to bone has begun to be appreciated. We employed multimodal strategy based on in-house PCa clinical samples, publicly available TCGA coho...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Colden, Melissa, Dar, Altaf A, Saini, Sharanjot, Dahiya, Priya V, Shahryari, Varahram, Yamamura, Soichiro, Tanaka, Yuichiro, Stein, Gary, Dahiya, Rajvir, Majid, Shahana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386393/
https://ncbi.nlm.nih.gov/pubmed/28125091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.15
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