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Transient expression of the Arf tumor suppressor during male germ cell and eye development in Arf-Cre reporter mice
The Arf tumor suppressor is expressed transiently during mouse male germ cell and eye development. Its inactivation compromises spermatogenesis as mice age and leads to aberrant postnatal proliferation of cells in the vitreous of the eye, resulting in blindness. In the testis, expression of p19(Arf)...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664155/ https://ncbi.nlm.nih.gov/pubmed/19339492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902310106 |
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