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Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway

Gigaxonin mutations cause the fatal human neurodegenerative disorder giant axonal neuropathy (GAN). Broad deterioration of the nervous system in GAN patients is accompanied by massive disorganization of intermediate filaments (IFs) both in neurons and many non-neuronal cells. With newly developed an...

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Detalhes bibliográficos
Main Authors: Cleveland, Don W., Yamanaka, Koji, Bomont, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664145/
https://ncbi.nlm.nih.gov/pubmed/19168853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp044
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