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Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway

Gigaxonin mutations cause the fatal human neurodegenerative disorder giant axonal neuropathy (GAN). Broad deterioration of the nervous system in GAN patients is accompanied by massive disorganization of intermediate filaments (IFs) both in neurons and many non-neuronal cells. With newly developed an...

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Bibliografske podrobnosti
Main Authors: Cleveland, Don W., Yamanaka, Koji, Bomont, Pascale
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664145/
https://ncbi.nlm.nih.gov/pubmed/19168853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp044
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