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Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway

Gigaxonin mutations cause the fatal human neurodegenerative disorder giant axonal neuropathy (GAN). Broad deterioration of the nervous system in GAN patients is accompanied by massive disorganization of intermediate filaments (IFs) both in neurons and many non-neuronal cells. With newly developed an...

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Autors principals: Cleveland, Don W., Yamanaka, Koji, Bomont, Pascale
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664145/
https://ncbi.nlm.nih.gov/pubmed/19168853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp044
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