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The role of the CD58 locus in multiple sclerosis

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system associated with demyelination and axonal loss. A whole genome association scan suggested that allelic variants in the CD58 gene region, encoding the costimulatory molecule LFA-3, are associated with risk of developing M...

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Detalhes bibliográficos
Main Authors: De Jager, Philip L., Baecher-Allan, Clare, Maier, Lisa M., Arthur, Ariel T., Ottoboni, Linda, Barcellos, Lisa, McCauley, Jacob L., Sawcer, Stephen, Goris, An, Saarela, Janna, Yelensky, Roman, Price, Alkes, Leppa, Virpi, Patterson, Nick, de Bakker, Paul I. W., Tran, Dong, Aubin, Cristin, Pobywajlo, Susan, Rossin, Elizabeth, Hu, Xinli, Ashley, Charles W., Choy, Edwin, Rioux, John D., Pericak-Vance, Margaret A., Ivinson, Adrian, Booth, David R., Stewart, Graeme J., Palotie, Aarno, Peltonen, Leena, Dubois, Bénédicte, Haines, Jonathan L., Weiner, Howard L., Compston, Alastair, Hauser, Stephen L., Daly, Mark J., Reich, David, Oksenberg, Jorge R., Hafler, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664005/
https://ncbi.nlm.nih.gov/pubmed/19237575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813310106
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