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Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model
Although p27 and p57 are structurally related cyclin-dependent kinase inhibitors (CKIs), and are thought to perform similar functions, p27 knockout (p27(KO)) and p57(KO) mice show distinct phenotypes. To elucidate the in vivo functions of these CKIs, we have now generated a knock-in mouse model (p57...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664003/ https://ncbi.nlm.nih.gov/pubmed/19276117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811712106 |
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