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Cyclin D2 Translocates p27 out of the Nucleus and Promotes Its Degradation at the G(0)-G(1) Transition

The nuclear export and cytoplasmic degradation of the cyclin-dependent kinase inhibitor p27 are required for effective progression of the cell cycle through the G(0)-G(1) transition. The mechanism responsible for this translocation of p27 has remained unclear, however. We now show that cyclin D2 dir...

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Bibliographic Details
Main Authors: Susaki, Etsuo, Nakayama, Keiko, Nakayama, Keiichi I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951473/
https://ncbi.nlm.nih.gov/pubmed/17452458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00862-06
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