Mitotic deregulation by survivin in ErbB2 overexpressing breast cancer cells contributes to Taxol resistance

PURPOSE: Taxol resistance remains a major obstacle to improve the benefit of breast cancer patients. Here we studied whether overexpression of ErbB2 may lead to mitotic deregulation in breast cancer cells via upregulation of survivin that confers Taxol resistance. EXPERIMENTAL DESIGN: ErbB2 over-exp...

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Hauptverfasser: Lu, Jing, Tan, Ming, Huang, Wen-Chien, Li, Ping, Guo, Hua, Tseng, Ling-Ming, Su, Xiao-hua, Yang, Wen-Tao, Treekitkarnmongkol, Warapen, Andreeff, Michael, Symmans, Fraser, Yu, Dihua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663973/
https://ncbi.nlm.nih.gov/pubmed/19228734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0954
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