Mitotic deregulation by survivin in ErbB2 overexpressing breast cancer cells contributes to Taxol resistance

PURPOSE: Taxol resistance remains a major obstacle to improve the benefit of breast cancer patients. Here we studied whether overexpression of ErbB2 may lead to mitotic deregulation in breast cancer cells via upregulation of survivin that confers Taxol resistance. EXPERIMENTAL DESIGN: ErbB2 over-exp...

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Detalhes bibliográficos
Main Authors: Lu, Jing, Tan, Ming, Huang, Wen-Chien, Li, Ping, Guo, Hua, Tseng, Ling-Ming, Su, Xiao-hua, Yang, Wen-Tao, Treekitkarnmongkol, Warapen, Andreeff, Michael, Symmans, Fraser, Yu, Dihua
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663973/
https://ncbi.nlm.nih.gov/pubmed/19228734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0954
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