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Association of two common single-nucleotide polymorphisms in the CYP19A1 locus and ovarian cancer risk

Although the role of estrogen in the etiology of ovarian cancer is uncertain, there is increasing evidence that hormone replacement therapy is a risk factor for ovarian malignancy. The production of estrogen involves the conversion of androgens via P450 aromatase, encoded by the CYP19A1 gene. Geneti...

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Hlavní autoři: Goodman, Marc T, Lurie, Galina, Thompson, Pamela J, McDuffie, Katharine E, Carney, Michael E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663409/
https://ncbi.nlm.nih.gov/pubmed/18667686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-08-0104
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