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Genetic Polymorphisms in the Paraoxonase 1 Gene and Risk of Ovarian Epithelial Carcinoma

Oxidative stress during successive ovulations increases the opportunity for DNA damage to ovarian epithelial cells and the potential for malignant transformation. Paraoxonase 1 (PON1) is an endogenous free radical scavenger that reduces oxidative stress. The association of two common functional sing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lurie, Galina, Wilkens, Lynne R., Thompson, Pamela J., McDuffie, Katharine E., Carney, Michael E., Terada, Keith Y., Goodman, Marc T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729507/
https://ncbi.nlm.nih.gov/pubmed/18708400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-0145
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