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c-Jun N-Terminal Kinase 1 Phosphorylates Myt1 To Prevent UVA-Induced Skin Cancer

The c-Jun N-terminal kinase (JNK) signaling pathway is known to mediate both survival and apoptosis of tumor cells. Although JNK1 and JNK2 have been shown to differentially regulate the development of skin cancer, the underlying mechanistic basis remains unclear. Here, we demonstrate that JNK1, but...

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Autors principals: Choi, Hong Seok, Bode, Ann M., Shim, Jung-Hyun, Lee, Sung-Young, Dong, Zigang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663297/
https://ncbi.nlm.nih.gov/pubmed/19204086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01508-08
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