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Intranasal Administration of Alpha Interferon Reduces Seasonal Influenza A Virus Morbidity in Ferrets

The type I interferon (IFN) response represents one of the first lines of defense against influenza virus infections. In this study, we assessed the protective potential of exogenous IFN-α against seasonal and highly pathogenic influenza viruses in ferrets. Intranasal treatment with IFN-α several ho...

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Detalhes bibliográficos
Main Authors: Kugel, Daniela, Kochs, Georg, Obojes, Karola, Roth, Joachim, Kobinger, Gary P., Kobasa, Darwyn, Haller, Otto, Staeheli, Peter, von Messling, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663257/
https://ncbi.nlm.nih.gov/pubmed/19193792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02453-08
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