Oseltamivir-Resistant Variants of the 2009 Pandemic H1N1 Influenza A Virus Are Not Attenuated in the Guinea Pig and Ferret Transmission Models

Oseltamivir is routinely used worldwide for the treatment of severe influenza A virus infection, and should drug-resistant pandemic 2009 H1N1 viruses become widespread, this potent defense strategy might fail. Oseltamivir-resistant variants of the pandemic 2009 H1N1 influenza A virus have been detec...

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Detalhes bibliográficos
Main Authors: Seibert, Christopher W., Kaminski, Michael, Philipp, Jennifer, Rubbenstroth, Dennis, Albrecht, Randy A., Schwalm, Folker, Stertz, Silke, Medina, Rafael A., Kochs, Georg, García-Sastre, Adolfo, Staeheli, Peter, Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953187/
https://ncbi.nlm.nih.gov/pubmed/20739532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01424-10
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