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Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against Pandemic Influenza

The emergence of a new influenza pandemic remains a threat that could result in a substantial loss of life and economic disruption worldwide. Advances in human antibody isolation have led to the discovery of monoclonal antibodies (mAbs) that have broad neutralizing activity against various influenza...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Limberis, Maria P., Adam, Virginie S., Wong, Gary, Gren, Jason, Kobasa, Darwyn, Ross, Ted M., Kobinger, Gary P., Tretiakova, Anna, Wilson, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596530/
https://ncbi.nlm.nih.gov/pubmed/23720583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006299
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