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Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against Pandemic Influenza

The emergence of a new influenza pandemic remains a threat that could result in a substantial loss of life and economic disruption worldwide. Advances in human antibody isolation have led to the discovery of monoclonal antibodies (mAbs) that have broad neutralizing activity against various influenza...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Transl Med
Prif Awduron: Limberis, Maria P., Adam, Virginie S., Wong, Gary, Gren, Jason, Kobasa, Darwyn, Ross, Ted M., Kobinger, Gary P., Tretiakova, Anna, Wilson, James M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596530/
https://ncbi.nlm.nih.gov/pubmed/23720583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006299
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