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Impaired Innate and Adaptive Immunity to Streptococcus pneumoniae and Its Effect on Colonization in an Infant Mouse Model

Streptococcus pneumoniae colonization and invasive disease peak around the third and first birthdays, respectively, and decline thereafter. While these declines are attributable in part to immunity acquired via natural exposure, maturation of innate immune responses may also be involved. A mucosally...

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Detalles Bibliográficos
Main Authors: Bogaert, Debby, Weinberger, Daniel, Thompson, Claudette, Lipsitch, Marc, Malley, Richard
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663178/
https://ncbi.nlm.nih.gov/pubmed/19168741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00871-08
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