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Impaired Innate Mucosal Immunity in Aged Mice Permits Prolonged Streptococcus pneumoniae Colonization

Streptococcus pneumoniae is a frequent asymptomatic colonizer of the nasopharyngeal niche and only occasionally progresses toward infection. The burden of pneumococcal disease is particularly high in the elderly, and the mechanisms behind this increased susceptibility are poorly understood. Here we...

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Detalhes bibliográficos
Main Authors: Krone, Cassandra L., Trzciński, Krzysztof, Zborowski, Tomasz, Sanders, Elisabeth A. M., Bogaert, Debby
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837976/
https://ncbi.nlm.nih.gov/pubmed/24082075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00618-13
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