Killed but Metabolically Active Bacillus anthracis Vaccines Induce Broad and Protective Immunity against Anthrax

Bacillus anthracis is the causative agent of anthrax. We have developed a novel whole-bacterial-cell anthrax vaccine utilizing B. anthracis that is killed but metabolically active (KBMA). Vaccine strains that are asporogenic and nucleotide excision repair deficient were engineered by deleting the sp...

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Detalhes bibliográficos
Main Authors: Skoble, Justin, Beaber, John W., Gao, Yi, Lovchik, Julie A., Sower, Laurie E., Liu, Weiqun, Luckett, William, Peterson, Johnny W., Calendar, Richard, Portnoy, Daniel A., Lyons, C. Rick, Dubensky, Thomas W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663168/
https://ncbi.nlm.nih.gov/pubmed/19168734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00530-08
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