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RICK Promotes Inflammation and Lethality after Gram-Negative Bacterial Infection in Mice Stimulated with Lipopolysaccharide

RICK (receptor-interacting protein-like interacting caspase-like apoptosis regulatory protein kinase), a serine-threonine kinase, functions downstream of the pattern recognition receptors Nod1 and Nod2 to mediate NF-κB and mitogen-activated protein kinase (MAPK) activation in response to specific mi...

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Bibliografiske detaljer
Main Authors: Park, Jong-Hwan, Kim, Yun-Gi, Núñez, Gabriel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663158/
https://ncbi.nlm.nih.gov/pubmed/19188356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01505-08
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