Lipopolysaccharide-Trap-Fc, a Multifunctional Agent To Battle Gram-Negative Bacteria

The family of Toll-like receptors (TLRs) plays a pivotal role in host defense against pathogens. However, overstimulation of these receptors may lead to uncontrolled general inflammation and eventually to systemic organ dysfunction or failure. With the intent to control overwhelming inflammation dur...

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Bibliographic Details
Main Authors: Groß, Philipp, Brandl, Katharina, Dierkes, Christine, Schölmerich, Jürgen, Salzberger, Bernd, Glück, Thomas, Falk, Werner
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708546/
https://ncbi.nlm.nih.gov/pubmed/19433546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00004-09
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