Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity against Flaviviruses

Imino sugars, such as N-butyl-deoxynojirimycin and N-nonyl-deoxynojirimycin (NNDNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II in the endoplasmic reticulum and exhibit antiviral activities against many types of enveloped viruses. Although these molecules have bro...

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Autors principals: Chang, Jinhong, Wang, Lijuan, Ma, Dongling, Qu, Xiaowang, Guo, Haitao, Xu, Xiaodong, Mason, Peter M., Bourne, Nigel, Moriarty, Robert, Gu, Baohua, Guo, Ju-Tao, Block, Timothy M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663077/
https://ncbi.nlm.nih.gov/pubmed/19223639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01457-08
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