A Novel Antiapoptotic Role for α(1)-Antitrypsin in the Prevention of Pulmonary Emphysema

Rationale: There is growing evidence that alveolar cell apoptosis plays an important role in emphysema pathogenesis, a chronic inflammatory lung disease characterized by alveolar destruction. The association of α(1)-antitrypsin deficiency with the development of emphysema has supported the concept t...

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Detalhes bibliográficos
Main Authors: Petrache, Irina, Fijalkowska, Iwona, Zhen, Lijie, Medler, Terry R., Brown, Emile, Cruz, Pedro, Choe, Kang-Hyeon, Taraseviciene-Stewart, Laimute, Scerbavicius, Robertas, Shapiro, Lee, Zhang, Bing, Song, Sihong, Hicklin, Dan, Voelkel, Norbert F., Flotte, Terence, Tuder, Rubin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
Assuntos:
C. Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662968/
https://ncbi.nlm.nih.gov/pubmed/16514110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200512-1842OC
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