The BTB-zinc finger transcriptional regulator, PLZF, controls the development of iNKT cell effector functions

Invariant Natural Killer T cell (iNK Tcell) have an innate immunity-like rapidity of response and the capacity to modulate effector functions of other cells. We show that the BTB-ZF transcriptional regulator, PLZF, is specifically expressed in iNKT cells. iNKT cells develop in the absence of PLZF, b...

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Auteurs principaux: Kovalovsky, Damian, Uche, Olisambu U., Eladad, Sonia, Hobbs, Robin M., Yi, Woelsung, Alonzo, Eric, Chua, Kevin, Eidson, Maggie, Kim, Hye-Jung, Im, Jin S., Pandolfi, Pier Paolo, Sant'Angelo, Derek B.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662733/
https://ncbi.nlm.nih.gov/pubmed/18660811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1641
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