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Synthesis and Screening of a Cyclic Peptide Library: Discovery of Small-Molecule Ligands against Human Prolactin Receptor

Prolactin receptor is involved in normal lactation and reproduction; however, excessive prolactin levels can cause various reproductive disorders such as prolactinomas. Small-molecule antagonists against the human prolactin receptor (hPRLr) thus have potential clinical applications and may serve as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Tao, Joo, Sang Hoon, Voorhees, Jeffrey L., Brooks, Charles L., Pei, Dehua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662701/
https://ncbi.nlm.nih.gov/pubmed/18234500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.01.015
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