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Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice

Type 2 diabetes is associated with accelerated atherogenesis, which may result from a combination of factors, including dyslipidemia characterized by increased VLDL secretion, and insulin resistance. To assess the hypothesis that both hepatic and peripheral insulin resistance contribute to atherogen...

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Detalhes bibliográficos
Main Authors: Han, Seongah, Liang, Chien-Ping, Westerterp, Marit, Senokuchi, Takafumi, Welch, Carrie L., Wang, Qizhi, Matsumoto, Michihiro, Accili, Domenico, Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662550/
https://ncbi.nlm.nih.gov/pubmed/19273907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36523
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