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PICK1 deficiency causes male infertility in mice by disrupting acrosome formation
Protein interacting with C kinase 1 (PICK1) is a peripheral membrane protein involved in protein trafficking, a function that has been well characterized in neurons. Here, we report that male mice deficient in PICK1 are infertile and have a phenotype resembling the human disease globozoospermia. The...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662547/ https://ncbi.nlm.nih.gov/pubmed/19258705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36230 |
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