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Loss of the Na(+)/H(+) exchanger NHE8 causes male infertility in mice by disrupting acrosome formation
Mammalian sperm feature a specialized secretory organelle on the anterior part of the sperm nucleus, the acrosome, which is essential for male fertility. It is formed by a fusion of Golgi-derived vesicles. We show here that the predominantly Golgi-resident Na(+)/H(+) exchanger NHE8 localizes to the...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5491771/ https://ncbi.nlm.nih.gov/pubmed/28476888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.784108 |
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