Učitavanje...
Targeted generation of DNA strand breaks using pyrene-conjugated triplex-forming oligonucleotides
Gene targeting by triplex-forming oligonucleotides (TFOs) has proven useful for gene modulation in vivo. Photoreactive molecules have been conjugated to TFOs to direct sequence-specific damage in double-stranded DNA. However, the photoproducts are often repaired efficiently in cells. This limitation...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662494/ https://ncbi.nlm.nih.gov/pubmed/18473480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7024029 |
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