Ligand-independent Homomeric and Heteromeric Complexes between Interleukin-2 or -9 Receptor Subunits and the γ Chain

Signaling via interleukin-2 (IL-2) and interleukin-9 receptors (IL-2R and IL-9R) involves heteromeric interactions between specific interleukin receptor subunits, which bind Janus kinase 1 (JAK1) and the JAK3 binding common γ chain (γ(c)). The potential existence and roles of homomeric and heteromer...

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Detalhes bibliográficos
Main Authors: Malka, Yaniv, Hornakova, Tekla, Royer, Yohan, Knoops, Laurent, Renauld, Jean-Christophe, Constantinescu, Stefan N., Henis, Yoav I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662275/
https://ncbi.nlm.nih.gov/pubmed/18829468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803125200
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