Formation of Stable Homomeric and Transient Heteromeric Bone Morphogenetic Protein (BMP) Receptor Complexes Regulates Smad Protein Signaling

The type I and type II bone morphogenetic protein receptors (BMPRI and BMPRII) are present at the plasma membrane as monomers and homomeric and heteromeric complexes, which are modulated by ligand binding. The complexes of their extracellular domains with ligand were shown to form heterotetramers. H...

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Bibliographic Details
Main Authors: Marom, Barak, Heining, Eva, Knaus, Petra, Henis, Yoav I.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103307/
https://ncbi.nlm.nih.gov/pubmed/21471205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210377
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