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Formation of Stable Homomeric and Transient Heteromeric Bone Morphogenetic Protein (BMP) Receptor Complexes Regulates Smad Protein Signaling

The type I and type II bone morphogenetic protein receptors (BMPRI and BMPRII) are present at the plasma membrane as monomers and homomeric and heteromeric complexes, which are modulated by ligand binding. The complexes of their extracellular domains with ligand were shown to form heterotetramers. H...

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Autori principali: Marom, Barak, Heining, Eva, Knaus, Petra, Henis, Yoav I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103307/
https://ncbi.nlm.nih.gov/pubmed/21471205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210377
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