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Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca(2+)-dependent cell survival and death

Calcium oscillations exert physiological control on mitochondrial energy metabolism and can also lead to mitochondrial membrane permeabilization and cell death. The outcome of the mitochondrial calcium signaling is altered by stress factors such as ceramide or staurosporine. However, the mechanism o...

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Detalhes bibliográficos
Main Authors: Roy, Soumya Sinha, Madesh, Muniswamy, Davies, Erika, Antonsson, Bruno, Danial, Nika, Hajnóczky, György
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662194/
https://ncbi.nlm.nih.gov/pubmed/19217411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.01.018
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