Pharmacokinetic interaction of flecainide and paroxetine in relation to the CYP2D6*10 allele in healthy Korean subjects

AIMS: The objectives were to evaluate the effect of CYP2D6 genetic polymorphism on the pharmacokinetics of flecainide, and also on the extent of drug interaction with paroxetine as a CYP2D6 inhibitor after a single oral administration in healthy subjects. METHODS: An open-label, two-period, single-s...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lim, Kyoung Soo, Cho, Joo-Youn, Jang, In-Jin, Kim, Bo-Hyung, Kim, JaeWoo, Jeon, Ji-Young, Tae, Yu-Mi, Yi, SoJeong, Eum, SoYoung, Shin, Sang-Goo, Yu, Kyung-Sang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
Soggetti:
Pharmacogenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661981/
https://ncbi.nlm.nih.gov/pubmed/18754843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03267.x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi