Population pharmacokinetic analysis for risperidone using highly sparse sampling measurements from the CATIE study

AIMS: To characterize pharmacokinetic (PK) variability of risperidone and 9-OH risperidone using sparse sampling and to evaluate the effect of covariates on PK parameters. METHODS: PK analysis used plasma samples collected from the Clinical Antipsychotic Trials of Intervention Effectiveness. A nonli...

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Bibliographische Detailangaben
Hauptverfasser: Feng, Yan, Pollock, Bruce G, Coley, Kim, Marder, Stephen, Miller, Del, Kirshner, Margaret, Aravagiri, Manickam, Schneider, Lon, Bies, Robert R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2008
Schlagworte:
Pharmacokinetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661978/
https://ncbi.nlm.nih.gov/pubmed/18771484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03276.x
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