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Determination of a benzamide histone deacetylase inhibitor, MS-275, in human plasma by liquid chromatography with mass-spectrometric detection
An analytical method was developed and validated for the quantitative determination of the histone deacetylase inhibitor MS-275 in human plasma. Calibration curves were linear in the concentration range of 1 to 250 ng/mL. Sample pretreatment involved a liquid-liquid extraction of 0.1 mL aliquots of...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661872/ https://ncbi.nlm.nih.gov/pubmed/19117815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2008.12.018 |
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