Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models

The tyrosine kinase JAK3 plays a well-established role during normal lymphocyte development and is constitutively phosphorylated in several lymphoid malignancies. However, its contribution to lymphomagenesis remains elusive. In this study, we used the newly identified activating JAK3A572V mutation t...

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Bibliografiske detaljer
Main Authors: Cornejo, Melanie G., Kharas, Michael G., Werneck, Miriam B., Bras, Séverine Le, Moore, Sandra A., Ball, Brian, Beylot-Barry, Marie, Rodig, Scott J., Aster, Jon C., Lee, Benjamin H., Cantor, Harvey, Merlio, Jean-Philippe, Gilliland, D. Gary, Mercher, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661862/
https://ncbi.nlm.nih.gov/pubmed/19139084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-06-164368
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