Association of the GNAS Locus with Severe Malaria

Functional studies have demonstrated an interaction between the stimulatory G protein alpha subunit (G-alpha-s) and the malaria parasite at a cellular level. Obstruction of signal transduction via the erythrocyte G-alpha-s subunit reduced invasion by P.falciparum parasites. We sought to determine wh...

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Detalhes bibliográficos
Main Authors: Auburn, Sarah, Diakite, Mahamadou, Fry, Andrew E., Ghansah, Anita, Campino, Susana, Richardson, Anna, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Griffiths, Michael J., Peshu, Norbert, Williams, Thomas N., Marsh, Kevin, Molyneux, Malcolm E., Taylor, Terrie E., Koram, Kwadwo A., Oduro, Abraham R., Rogers, William O., Rockett, Kirk A., Haldar, Kasturi, Kwiatkowski, Dominic P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661463/
https://ncbi.nlm.nih.gov/pubmed/18951142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0575-8
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