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Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor Activation: CONSTITUTIVE ENHANCEMENT OF CALCIUM SIGNALING IN MCF-7 TUMOR CELLS
Sigma-1 receptor (sigma-1R) agonists enhance inositol 1,4,5-trisphosphate (IP(3))-dependent calcium release from endoplasmic reticulum by inducing dissociation of ankyrin B 220 (ANK 220) from the IP(3) receptor (IP(3)R-3), releasing it from inhibition. MCF-7 breast tumor cells express little or no s...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2661391/ https://ncbi.nlm.nih.gov/pubmed/18539593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802099200 |
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