Isoform-specific Regulation of the Inositol 1,4,5-Trisphosphate Receptor by O-Linked Glycosylation

The inositol 1,4,5-trisphosphate receptor (InsP(3)R), an intracellular calcium channel, has three isoforms with >65% sequence homology, yet the isoforms differ in their function and regulation by post-translational modifications. We showed previously that InsP(3)R-1 is functionally modified by O-...

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Bibliographic Details
Main Authors: Bimboese, Patricia, Gibson, Craig J., Schmidt, Stefan, Xiang, Wanqing, Ehrlich, Barbara E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091177/
https://ncbi.nlm.nih.gov/pubmed/21383013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.206482
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