A carregar...

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance

The switch of cellular metabolism from mitochondrial respiration to glycolysis is the hallmark of cancer cells and associated with tumor malignancy. However, the mechanism of this metabolic switch remains largely unknown. Herein, we reported that hypoxia-inducible factor-1 (HIF-1) induced pyruvate d...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lu, Chun-Wun, Lin, Shih-Chieh, Chen, Ko-Fan, Lai, Yen-Yu, Tsai, Shaw-Jenq
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661383/
https://ncbi.nlm.nih.gov/pubmed/18718909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803508200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!