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Transcriptional repression of human cad gene by hypoxia inducible factor-1α

De novo biosynthesis of pyrimidine nucleotides provides essential precursors for DNA synthesis and cell proliferation. The first three steps of de novo pyrimidine biosynthesis are catalyzed by a multifunctional enzyme known as CAD (carbamoyl phosphate synthetase-aspartate carbamoyltransferase-dihydr...

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Bibliografische gegevens
Hoofdauteurs: Chen, Ko-Fan, Lai, Yen-Yu, Sun, H. Sunny, Tsai, Shaw-Jenq
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1214551/
https://ncbi.nlm.nih.gov/pubmed/16155188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki839
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